Isolation and Identification of Two Taxane Diterpenoid Compounds
- VernacularTitle:两种紫杉烷类二萜化合物的分离鉴定
- Author:
Zhongqiang ZHOU
;
Xingguo MEI
- Publication Type:Journal Article
- From:
Journal of China Pharmaceutical University
2001;(3):190-192
- CountryChina
- Language:Chinese
-
Abstract:
AIM Taxane diterpenoid compounds are expected to be isolated from Taxus chinensis cell cultures. METHODS Cell cultures were extracted with 95% alcohol, distributed by different solvents, isolated via column chromatography on silica gel and purified by crystallization. RESULTS AND CONCLUSION Two taxane diterpenoid compounds were isolated from Taxus chinensis cell cultures for the first time.Their structures were identified as 14β-(2-methylbutyryl)oxy-2α,5α, 10β-triacetoxytaxa-4(20),11-diene(1) and 5α-(cinnamoyl)oxy-7β,9α,10β,13α-tetraacetoxytaxa-4(20),11-diene(2) respectively.
