Study on the preparation of piroxicam films
- VernacularTitle:吡罗昔康贴剂的研制
- Author:
Ping ZHOU
- Publication Type:Journal Article
- From:
Chinese Pharmaceutical Journal
2001;(3):172-173
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE To prepare the piroxicam films and study its characteristics of transdermal delivery.METHODS Different high polymers were employed to prepare piroxicam films.Rat abdomen skin and modified Franz diffusion cells were used in the drug penetration tests and release tests.The percutaneous penetration rate was investigated.RESULTS The release rate of piroxicam films was 64.31 μg*cm-2*h-1.The in vitro permeation rate was 14.86 μg*cm-2*h-1.The percutaneous penetration rate was 11.94 μg*cm-2*h-1.CONCLUSION Piroxicam films was developed.
