Prognostic significance of CD57+ cell level and pTNM staying system in patients with laryngeal cancer
10.3969/j.issn.1001-1781.2001.02.011
- VernacularTitle:术后临床分期及CD57+细胞水平对喉癌患者生存预后的评价
- Author:
Meihua ZHENG
;
Xinyong LUAN
- Publication Type:Journal Article
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2001;(2):73-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the prognostic value of the pTNM clinical staying system,as well as the CD57+ cells level in peripheral blood samples of the patients with laryngeal carcinoma.Method:The CD57+ cells level of peripheral blood was determined with SAP method in 34 patients with laryngeal carinoma and 16 normal subjects.The pTNM clinical stage was T1-2in 13,T3-4 in 21;pN+ in 10, pN0 in 24;supraglottis in 8,glottis in 23;hypoglottis in 3;pathologic differentiation G1 in 11,G2,3 in 23.Result:The CD57+ cells level significantly increased (pN+ vs.pNO).In the 12nd month actual survival were significantly different (T1,2 vs.T3,4,pN0 vs.pN+,G1 vs G2、3,supraglottis vs.glottis and hypoglottis,CD57+≥15% vs.CD57+<15%).In the 24th month and 36th month actual survival were significantly different (pN0 vs.pN+,G1 vs G2、3,supraglotisvs.glottis and hypoglottis,CD57+≥15% vs.CD57+<15%).In the 48th month actual survival were significantly different only (pN0 vs.pN+,supraglottis vs.glottis and hypo glottis,CD57+≥15% vs.CD57+<15%).Conclusion:These results suggested that the assessment of pTNM system and the CD57+ cells level have significance for prognosis of patients with laryngeal carcinoma.