Lymph node marginal zone B-cell lymphoma:A clinicopathological analysis
10.3969/j.issn.1001-7399.2001.02.002
- VernacularTitle:原发淋巴结边缘区淋巴瘤临床病理分析
- Author:
Tianrong XU
;
Zhihong ZHANG
;
Qinhe FAN
;
Zhaoxun ZHENG
- Publication Type:Journal Article
- From:
Chinese Journal of Clinical and Experimental Pathology
2001;(2):99-102
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To study the pathological characteristics, diagnostic criteria and differential diagnoses of the lymph node marginal zone B-cell lymphoma (LMZL), for the clinical treatment and prognosis. Methods Histopathology and immunohistochemistry(ABC method) were used in ten cases of LMZL. Results There were six male and four female. Lymphadenopathy was the main symptom in all of the cases, of which none had hepatosplenomegaly and abnormal lymphocytes in the peripheral blood. Two of them were marginal zone type, four nodular type, two diffuse type and two blastic type morphologically. Five of them were central cell like (CCL) type, six monocytic B-cell (MBC), two of them lymphoplasmacytic and two blastic histopathologically. Immunophenotyping was done in ten cases and supported the diagnosis. Conclusions LMZL and MALT-type lymphoma have similar appearance, immunophenotype and cell origin. Based on the structural features, LMZL is a special entity.
