Lymphadenitis in cat scratch disease(CSD):A clinicopathological study
10.3969/j.issn.1001-7399.2001.02.008
- VernacularTitle:猫抓病性淋巴结炎的临床病理分析
- Author:
Xia GE
;
Qun XIE
;
Zenong CHENG
;
Min YAO
;
Dechun LIU
;
Dichen LI
- Publication Type:Journal Article
- From:
Chinese Journal of Clinical and Experimental Pathology
2001;(2):120-22
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To study the main points of the diagnosis and differential diagnosis of the lymphadenitis in CSD. Methods Expression of CD45, CD3 and CD68 were evaluated immunohistochemically (S-P method). Results Five cases of microabscess in early stage and 21 cases of microabscess-granuloma were found. The histologic features were the formation of microabscess and granuloma. The early microabscess in the lymphnodes were surounded by B lymphocytes (CD20+) and macrophages (CD68+). The typial microabscess granuloma were surrounded by epitheloid cells (CD68+) and CD3 positive T lymphocytes. Conclusion The main characteristic of the lymphadenitis of cat scratch disease is the formation of granuloma with microabscess. The immumohistochemical markers are useful to distinguish the proliferative cell types. This lesion may result from bacterial infection which induces the cell immune reaction.
