Primary lymphoma of bone:A clinicopathologic and immunohistochemical observation
10.3969/j.issn.1001-7399.2001.02.011
- VernacularTitle:原发性骨恶性淋巴瘤临床病理及免疫表型观察
- Author:
Zhihua WANG
;
Xiaoqiu WANG
;
Xuesong FANG
;
Junyang NIU
;
Rongxuan CHENG
- Publication Type:Journal Article
- From:
Chinese Journal of Clinical and Experimental Pathology
2001;(2):130-132
- CountryChina
- Language:Chinese
-
Abstract:
Purposes To observe the clinicopathologic and immunohistochemical features of primary lymphoma of bone(PLB). Methods Eight cases of PLB were investigated by light microscopy and immunohistochemical staining. Results The mean age of eight cases of PLB was 51 years. Radiographs of all cases showed the lytic lesions or osteoporosises; All the cases were diffuse non-Hodgkins lymphomas(NHL), including 4 large cell lymphomas (centroblastic, CB), 2 centrocytic(CC), one mixed cell (CB-CC ) and one lymphoplasmacytic (LP); Immunohistochemical features revealed 6 cases of B-cell, 2 T-cell. Conclusions The peak incidence for PLB is in the 5th decade with the radiologic appearance of lytic lesions or osteoporosises. All tumors are the diffuse NHL, including mainly large cell lymphomas and immunophenotypic features of B-cell lymphomas. Immunohistochemistry is helpful in the differential diagnosis of PLB.
