Injecting Kanseran into Tumor Mass via Fibrobronchoscope in Combination with Chemotherapy for Treatment of Advanced Non-small-cell Lung Cancer
10.3870/j.issn.1004-0781.2001.02.024
- VernacularTitle:A群链球菌联合化疗治疗非小细胞肺癌19例
- Author:
Jie TAN
;
Zhong LIN
;
Shuhua ZHUANG
;
Yi SHANG
;
Kuifeng LIU
- Publication Type:Journal Article
- From:
Herald of Medicine
2001;(2):108-109
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the therapeutic effect and toxicity of local Kanseran injection in combination with chemotherapy in advanced NSCLC patients.Methods:A total of 18 cases was recruited in this study. After desensitization,Kanseran injection was injected into tumor mass through fibrobronchoscope,2 mg every time,once per week. Meanwhile,MVP regimen was administered.Results:Of the 18 patients,1 was completely relieved,7 cases were partially relieved. The response rate was 44.4%. After treatment,when examined by fibrobronchoscope the tumor masses of 15 patients became smaller. The main side effects were fever,alopecia and gastrointestinal reaction,which were mild and tolerable.Conclusion:Local Kanseran injection into tumor mass in conjunction with chemotherapy is effective and safe in the treatment of advanced NSCLC patients with bronchus obstruction.
