The clinical significance of serum TNF-α and IL-6 level in lung cancer patients
10.3969/j.issn.1000-1492.2001.01.014
- VernacularTitle:肺癌患者血清TNF-α和IL-6水平观察及临床意义
- Author:
Xin SUN
- Publication Type:Journal Article
- From:
Acta Universitatis Medicinalis Anhui
2001;(1):45-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change and clinical implications of tumor necrosis(TNF-α) and interleukin-6(IL-6) in the lung cancer patients. Methods Serum TNF-α and IL-6 level in 55 of lung cancer cases and 40 in normal control group were assayed by ELISA. Results Serum TNF-α and IL-6 level were significantly higher in the lung cancer patients than in normal control(P<0.01). The activity of TNF-α and IL-6 in serum of the no operational patients (with lymphanode matastasis) was higher than the recurrent patients of post-operation (P<0.01). Conclusion The activity of serum TNF-α and IL-6 may be associated with development of the lung cancer. The determination of TNF-α and IL-6 levels in serum can help to observe the lung cancer state as a assistant monitor methods.
