Significance of basophil histamine release assays in chronic urticaria
10.3969/j.issn.1671-8348.2001.01.012
- VernacularTitle:嗜碱粒细胞组胺释放试验检测抗高亲和力IgE抗体及其受体
- Author:
Rongqing LIU
;
Renshan SUN
- Publication Type:Journal Article
- From:
Chongqing Medicine
2001;(1):27-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Investigate the pathogenesis of chronic idiopathic urticaria.Methods Basophil histamine release assay was utilized.Result 15 of 32 cases(46.9%)had increased serum histamine releasing activities. This implied that anti-FcεR1 and anti-IgE autoantibodies existed in the sera of some patients with chronic idiopathic urticaria.Conclusion It suggested that autoimmunity might take part in the occurrence of some patients with chronic idiopathic urticaria.