Pathologic quantitative analysis of atherosclerrosis in rabits to verify introvensional ultrasonographic results
10.3969/j.issn.1001-7399.2001.01.017
- VernacularTitle:兔动脉粥样硬化病理定量分析对血管内超声显像结果的验证
- Author:
Dongmei WEI
;
Dade CAO
;
Hongying ZHAO
- Publication Type:Journal Article
- From:
Chinese Journal of Clinical and Experimental Pathology
2001;(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
To verify the role of introvascular ultrasound(IVUS) in diagnosis of atherosclerosis. MethodsINUS wasused to measure the position, quality and the thickness of the plaque in the elastic artery and biopsy materials. After using HE andHart stains, a micrometer was used to measuse the thickness of plaques and arterious walls. And electron microscopy was used to ob serve the pathological changs of the plaque. ResultsBy histological observation compared with IVUS, the conformable rate of plaque anmounted to 94%. The plaque could be seen in 12 sites of control group. Among 33 sites, 32 plaques were found pathologic exmination while IVUS showed 30 plaques in the experimental group. The two methods had a gcod correlation on the thick measurement of plaque and the media( r = 0.835, P＜0.05 and r = 0.814, P＜ 0.05). But they had a poor correlation on the measurement of the intirna( r = 0.055). ConclusionsBy pathological examination and the quantitative analysis, IVUS can obtain the common purpose in diagnosing atherosclerosis and measuring the media thickness. But it can not be used in measurement of the intima.
