Studies of the Active Component Parts of APN on the Antiplatelet Aggregation
10.3870/j.issn.1004-0781.2001.01.003
- VernacularTitle:穿心莲抗血小板聚集活性物质研究
- Author:
Yunhai LIU
;
Huafeng FANG
;
Shuiping DING
;
Hongwei WANG
- Publication Type:Journal Article
- From:
Herald of Medicine
2001;(1):6-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This paper was designed to reveal the active ingredients to inhibit platelet aggregation in Andregraphis Paniculata Ness (APN). Methods:Separating the active component parts of APN on the antiplatelet aggretion by extraction of organic solvent, chemical separation and silica column chromatography step by step, simultaneously comparing the effect of samples in APN on the antiplatelet aggretion induced by ADP, so that we can find the more active components. Results:We find the acid components in chlorlform parts (F021) show more active on the antiplatelet aggretion, farthermore we think we can obstain pure chemicals on the antiplatelet aggretion in F0212 and F0214. Conclusions:The active components on antiplatelet aggretion of APN can be prepared by separation step by step.
