A CLINICAL STUDY OF THE DISTRIBUTION OF METASTATIC CANCER SITES IN LIVER OF DIFFERENT LOCATIONS OF COLORECTAL CARCINOMA
10.3781/j.issn.1000-7431.2001.01.021
- VernacularTitle:不同部位大肠癌肝转移分布的临床研究
- Author:
Jinsong ZHAO
- Publication Type:Journal Article
- From:
Tumor
2001;(1):61-62
- CountryChina
- Language:Chinese
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Abstract:
Objective To study the distribution of metastatic cancer sites in liver of different loctions of colorectal carcinoma as a guide for treatment. Methods According to the blood supply from the superior a and inferior mesenteric arteries we used the splenic flexure as the middle coordinate and divided the large intestine into right and left two halves and then the sites of metastatic cancers were observed carefully. Results When the venous blood streams from the superior and inferior mesenteric veins entered the portal vein they were not well mixed. This phenomina influenced the distribution of the metastatic lesions: primary cancer in right half of large intestine metastasied to right lobe of liver in 87.9%(58/66) of cases, and left half primary cancers metastasised to both right and left lobes of liver without regular rule. Cancers of sigmoid colon had high rate of liver metastases of 69.3% in total number of colorectal carcinoma with liver metastasis (203/293). Conclusion The results of this study suggest that besides chemotherapy given through hepatic artery, the portal vein route of administration of chemotherapeutic drugs may be more reasonable and effective.
