The expression of transforming growth factor α and its receptor in nasal polyps
10.3969/j.issn.1001-1781.2000.11.001
- VernacularTitle:转化生长因子α及其受体在鼻息肉中的表达
- Author:
Fuquan CHEN
;
Weiguo HUANG
;
Li QIAO
;
Hongyan JIANG
- Publication Type:Journal Article
- Keywords:
Nasal polyp Transforming growth factor-α Epidermal growth factor receptor Proliferatingcell nuclear antigen
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2000;(11):483-484
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the possible role of expression of TGFα and EGFR in nasal polyps and its re-lationship with PCNA labeling index. Method: Specimens from 20 patients of nasal polyps were studied with im-munohistochemical technique. Result: The expression of TGFα,EGFR and PCNA were increased in the epitheli-um, gland cells and inflammatory cells of nasal polyps. There was a close correlation between the intensities ofTGFα,EGFR and PCNA. Conclusion: TGFα may play a key role in epithelial cell proliferation in nasal polyps.
