Detection of Epstein-Barr virus DNA in fine needle aspiration specimen from cervical lymphnodes with polymerase chain reaction
10.3969/j.issn.1001-1781.2000.10.009
- VernacularTitle:聚合酶链反应对颈部肿块的EBV检测
- Author:
Zhengxiu LEI
;
Qiurun LIU
;
Ping YUAN
- Publication Type:Journal Article
- Keywords:
Polymerase chain reaction Nasopharyngeal neoplasms Epstein-Barr virus Lymphatic metastasis
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2000;(10):454-455
- CountryChina
- Language:Chinese
-
Abstract:
Objective:For the diagnosis of occult nasophargngeal carcinoma. Method:Epstein-Barr virus in 58 fine needle aspirations from cervical metastatic lymphnodes were detected with polymerase chain reaction. Result: The positive reaction was found in 28/35 metastatic carcinoma samples from middle or upside neck. Negative reaction was found in 3 lymphomas,4 metastatic carcinomas in clavicular superior lymphnodes and 15/ 16 inflammatory diseases of cervical lymphnodes. The sensibility of this method for the diagnosis of nasopharyngeal carcinoma was 89.3%. The specificity was 86.7%. Conclusion: The detection of Epstain-Barr virus in metastatic carcinoma from cervical lymphnodes had some clinical values for the diagnosis of occult nasopharyngeal carcinoma.
