Successful allogeneic bone marrow transplantation for childhood-onset refractory anemia with ringed sideroblasts.
10.3346/jkms.2000.15.1.103
- Author:
Hoon KOOK
1
;
Chan Jong KIM
;
Won Sang YOON
;
Dong Wook RYANG
;
Tai Ju HWANG
Author Information
1. Department of Pediatrics, Hematopoietic Stem Cell Transplant Program, Chonnam National University Medical School, Kwangju, Korea. hoonkook@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Anemia Sideroblastic;
Myelodysplastic Syndromes;
Child;
Bone Marrow Transplantation;
Transplantation, Homologous
- MeSH:
Anemia, Refractory/therapy*;
Anemia, Sideroblastic/therapy*;
Bone Marrow Transplantation*;
Case Report;
Child;
Human;
Male;
Transplantation, Homologous
- From:Journal of Korean Medical Science
2000;15(1):103-104
- CountryRepublic of Korea
- Language:English
-
Abstract:
Refractory anemia with ringed sideroblasts (RARS) is an extremely rare type of myelodysplastic syndrome in children. We describe a 10-year-old boy with RARS presented with pancytopenia. He remained relatively stable with only a few transfusions until age of 20 years, when he underwent an allogeneic bone marrow transplantation (BMT) because of increased transfusion requirements. He remains in complete chimeric state at 20 months posttransplant with normal hematologic parameters. To our knowledge, this is the first description of successful BMT in a patient with childhood-onset RARS. The indication of BMT for this rare disorder in children is discussed.
