Clinical study for mouse nerve growth factor on treating herpes zoster

VernacularTitle:鼠神经生长因子治疗带状疱疹的临床研究
Author: Yan WAN ; Yahui JIANG ; Herong YANG ; Xingwen XU
Publication Type:Journal Article
Keywords: Nerve growth factor; Mice; Herpes zoster
From: Chinese Journal of Postgraduates of Medicine 2013;(15):21-22
CountryChina
Language:Chinese
Abstract: Objective To observe the effect of mouse nerve growth factor (mNGF) on treating herpes zoster.Methods The 64 patients with herpes zoster were divided into treatment group and control group by random digits table with 32 cases each.The control group received only routine treatment,the treatment group based on routine treatment combined with mNGF 30 μ g,both groups were treated 14 days.Pain changes of two groups were observed in once every 5 days,a total of 1 month.Results The times of pain to lessen and the pain to vanish of treatment group were (4.36 ± 2.01) and (12.29 ± 1.98) d,those of control group were (7.23 ±3.57) and (20.36 ±2.24) d,there were significant differences (t =5.21 and 8.37,P ＜0.01).The effective rate of treatment group was significantly higher than that of control group [96.9％(31/32) vs.71.9％(23/32),P＜0.05].Conclusion mNGF combined with routine treatment can significantly shorten the course of nerve injury and improve the prognosis with few adverse reactions.