Production and functional testing of polyurethane valve of the pediatric Luo-Ye pump
10.3969/j.issn.2095-4344.2013.31.005
- VernacularTitle:婴幼儿罗叶泵聚氨酯瓣膜的制作及功能测试**★
- Author:
Yueheng WU
;
Huanlei HUANG
;
Ruixin FAN
;
Zhoucuo QI
;
Liming YAO
;
Changli WU
;
Pinglan LU
;
Anheng CHENG
;
Xuejun XIAO
- Publication Type:Journal Article
- Keywords:
organ transplantation;
heart-lung transplantation;
ventricular assist device;
Luo-Ye pump;
polyurethane;
trefoil valve;
fatigue resistance;
cardiac device;
National Natural Science Foundation of China
- From:
Chinese Journal of Tissue Engineering Research
2013;(31):5607-5612
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:The mechanical valves used in the adult Luo-Ye pump have a large size and great destruction to blood, which are not suitable for infant ventricular assist pump. Therefore, designing and producing a high molecular valve with smal size and low incidence of thrombosis is a research hotspot. OBJECTIVE:To design and produce a valve of 20 mL infant Luo-Ye pump, and to test its basic functions and fatigue properties. METHODS:The size and shape of valve was designed with MASTERCAM software, polyurethane valve was obtained through producing the valve model and plastic injection;the static leakage, pressure drop and fatigue resistance of polyurethane valve were tested according to the ISO5840 requirements. RESULTS AND CONCLUSION:The polyurethane trefoil valve was produced, but the failure rate of plastic injection was high;the basic function of the trefoil valve met the ISO5840 requirements bascial y;after continuously operated 1.0×107 times, stroke volume of 20 mL Luo-Ye pump was changed 5.2%, and two polyurethane valves and valve leaflets did not change and damage. Polyurethane trefoil valve was designed and produced successful y;polyurethane valves could meet the needs of 20 mL Luo-Ye pump, which already have the ability to clinical trials.
