Comparison of the effect of Yanhuning and ribavirin in the treatment of children with acute upper respiratory tract infection
10.3760/cma.j.issn.1008-6706.2013.08.012
- VernacularTitle:炎琥宁与利巴韦林治疗小儿急性上呼吸道感染效果比较
- Author:
Liyan ZHAO
- Publication Type:Journal Article
- Keywords:
Yanhuning;
Ribavirin;
Children;
Acute Upper Respiratory Infection;
Immunity
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(8):1148-1150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical effect and safety of children with acute upper respiratory tract infection treated with Yanhuning and ribavirin.Methods 182 cases with acute upper respiratory tract infection treated were selected and divided into observation group and control group randomly.All children were given general symptomatic and supportive treatment.Yanhuning was added in observe group,10mg · kg-1 · d-1,ivgtt,qd,and ribavirin was added in control group,10mg · kg-1 · d-1,ivgtt,qd.Changes and disappearance time of clinical symptoms were observed.Results 89 cases (97.80％) were treated effectively in observation group,while 73 cases (80.22％) in control group,the efficacy of Yanhuning was higher than that of ribavirin (P ＜ 0.05).The time of clinical symptoms disappeared and blood examination recovering were shorter in observation group than that in control group (all P ＜ 0.05).Scores of fever and cough in observation group were (2.90 ± 0.04) and (2.87 ± 0.06),while those in control group were (2.37 ± 0.11) and (2.26 ± 0.13).The scores in observation group were higher than those in control group (all P ＜ 0.05).Conclusion Yanhuning applied in children with acute upper respiratory tract infection treatment is efficacy and safe,and it could adjust systemic immunity of children,which is worthy of clinical application.
