Patient with Malignant Granular Cell Tumor Treated with Sunitinib Malate.
- Author:
Su Jin LEE
1
;
Ji Hyun KIM
;
Hyun Wook CHO
;
Gyeong Jae NA
;
Han Jo KIM
;
Sang Byung BAE
;
Kyu Taek LEE
Author Information
1. Division of Hematology-Oncology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. hzmd@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Malignant;
Granular cell tumor;
Sunitinib
- MeSH:
Granular Cell Tumor;
Humans;
Indoles;
Pyrroles;
Sarcoma
- From:Soonchunhyang Medical Science
2012;18(1):66-69
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant granular cell tumors (MGST) are extremely rare, high-grade sarcoma of schwann cell origin. They often metastasize and are associated with short survival. We described a patient with recurred MGST after wide marginal excision followed by chemotherapy. The histologic findings revealed relapsed MGST containing rich vascular structure. The patient was treated with sunitinib malate (50 mg/day) for three weeks. Because sunitinib malate has a potent antiangiogenic property, we surmised that it might be effective against this type of malignancy. However, he died due to progression of tumor after six weeks. Here, we report it along with the corresponding literature.
