Epidemiological feature of respiratory syncytial virus in hospitalized children in Suzhou
10.3969/j.issn.1000-3606.2013.08.006
- VernacularTitle:苏州地区住院儿童呼吸道合胞病毒流行特点分析
- Author:
Fengguo WAN
;
Xuelan ZHANG
;
Xuejun SHAO
;
Zhenghua JI
- Publication Type:Journal Article
- Keywords:
respiratory syncytial virus;
epidemiological;
climate;
child
- From:
Journal of Clinical Pediatrics
2013;(8):723-725
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate the epidemiological feature of respiratory syncytial virus (RSV) in hospitalized children with acute respiratory infection. Methods A total of 28 871 children with acute respiratory tract infection from Janu-ary 2007 to December 2011 were enrolled in the study. Nasopharyngeal aspirates were obtained from the respiratory tract by aseptic vacuum aspiration. Direct immuno-lfuorescence assay was used to detect RSV antigen. Correlation between RSV posi-tive rate and meteorological data including mean air temperature and total monthly rainfall, etc. was analyzed. Results The peak infection seasons of RSV during 2007-2010 were winter and spring in Suzhou, while in 2011 the infection rate of RSV was increased since July. The positive rates of RSV during winter and spring in 2007-2008, 2008-2009, 2009-2010 and 2010-2011 were 38.57%, 19.86%, 29.73%and 30.79%, respectively, with signiifcant difference (χ2=176.85, P<0.001). From July to September in 2011, the positive rate of RSV was 5.74%, 21.09%and 31.15%, respectively, higher than that of the same period from 2007 to 2010 (χ2=8.06~405.43, all P<0.05). The positive rate of RSV was negatively correlated with mean temperature, volume of rainfall, duration of sunshine and wind velocity (r=-0.799~-0.214, all P<0.05). Only mean temperature had a signiifcant impact on RSV activity by a stepwise multiple regression (P<0.001). Conclusions The date indicated that RSV was still an important etiological agent for acute lower respiratory infection in infants and young children in Suzhou area during winter and spring. The incidence of RSV was associated with the climate in Suzhou.
