miR-203 and cancer
10.3760/cma.j.issn.1673-422X.2013.06.006
- VernacularTitle:微小RNA-203与肿瘤
- Author:
Qiufeng QI
;
Yongping LIU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
MicroRNA-203;
Target gene
- From:
Journal of International Oncology
2013;(6):419-421
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA(miR)-203 is a stemness-inhibiting miRNA that adjusts the epithelioid cell differentiation by restricting the expression of stemness-related transcription factor.Its abnormal expression has been detected in several types of human cancers,including bladder cancer,breast cancer,colon cancer and pancreatic cancer.miR-203 plays a critical role in the tumor genesis and development by regulating cell proliferation,differentiation and apoptosis.
