Oncogene Pim-1 and tumor
10.3760/cma.j.issn.1673-422X.2013.06.002
- VernacularTitle:癌基因Pim-1在肿瘤中的研究
- Author:
Jiajie XU
;
Kejing WANG
;
Minghua GE
- Publication Type:Journal Article
- Keywords:
Oncogene;
Serine threonine protein kinase;
Apoptosis
- From:
Journal of International Oncology
2013;(6):406-409
- CountryChina
- Language:Chinese
-
Abstract:
Oncogene Pim-1 has a close relationship with the occurrence and development of several tumours.It is involved in a number of signal transduction pathways and regulates the expression of the downstream biological factors or acts synergistically with other oncogenes.Pim-1 plays an important role in the clinical diagnosis,treatment and prognosis of some tumors,and provides a new potential target in the chemotherapy of tumors.Recently,Pim-1-targeting treatment strategy has be a research hotspot and it would be used for cancer clinical treatment hopefully.
