The self-regulation of impulsivity in children with ADHD:the ERPs P3 analysis in Go/NoGo task
10.3969/j.issn.1000-3606.2010.11.001
- VernacularTitle:注意缺陷多动性障碍儿童冲动的自我调控:Go/NoGo任务的ERPs P3分析
- Author:
Jinsong ZHANG
;
Yan WANG
;
Chonghuai YAN
;
Rugang CAI
;
Fang REN
- Publication Type:Journal Article
- Keywords:
serf-regulation;
impulsivity;
event related potentials;
Go/NoGo;
P3
- From:
Journal of Clinical Pediatrics
2010;(11):1001-1008
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the deficiency of serf-regulation in impulsivity children with attention deficit hyperactivity disorder(ADHD)based on both procedures of action and inhibitory control.The event related potentials(ERPs)component P3 in Go/NoGo tasks was analyzed.Methods There were 15 impulsive children with ADHD and15 normal children in control group.Their age was from seven years old to eleven years old.The Go/NoGo stimulate-response model was adopted in the ERPs test.The occurrence of Go and NoGo trials was equal probability(each of 50%).Results(1)The high impulsive children had slower Go-RTs(reaction times)in making correct response than normal children,tended to be faster of NoGo-RTs in making error response and had lower correct rate.(2)P3amplitudes in both control and ADHD children had the tendency of Go-P3 > NoGo-P3,especially significant at CPz and Pz in ADHD children,showed the trend of parietal central to parietal maximum and the frontal minimum,The NoGo-P3 amplitude of ADHD group was smaller especially significant at FCz and Cz,and tended to be smaller than control on left hemisphere.(3)NoGo-P3 is smaller in impulsive children with ADHD than normal children,most significant at FCz.(4)Brain maps showed that impulsive children with ADHD were lower activation significantly in the right frontal area.Conclusions The efficiency of ADHD in action is lower.The behavior regulation in impulsive children is limited.Go/NoGo-P3 reflects action processing and attention.The left parietal lobe to central area is engaged much more in action procedure and attention.This research shows the evidence of weakened parietal cortex and right frontal cortex in impulsive children with ADHD.
