Change of constituents in Cortex Phellodendri after processing
- VernacularTitle:黄柏炮制后化学成分转化研究
- Author:
Dongli QI
;
Tianzhu JIA
;
Lian LIAN
- Publication Type:Journal Article
- Keywords:
Cortex Phellodendri;
processing;
berberine hydrochloride;
berberrubine;
HPLC
- From:
Chinese Traditional Patent Medicine
2010;(3):443-447
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To research the chemical modification from berberine hydrochloride to berberrubine in Cortex Phellodendri before and after processing.METHODS:Berberrubine was isolated by column chromatography and the contents of berberine hydrochloride and berberrubine in different processed Cortex Phellodendri were determined by HPLC.RESULTS:With increacing processing temperature and time,part of berberine hydrochloride became berberrubine in processed Cortex Phellodendrin,and berberrubine content decreased under the condition of high temperature operation or overtime processing.CONCLUSION:The experimental data shows that the processed Cortex phellodendri has the maximum average content of berberrubine as processing temperature is maintained as 180℃ for 40 min.
