Antipyretic effect of Qingqi Liangying Injection
- VernacularTitle:清气凉营注射液的解热作用
- Author:
Xuehong GU
;
Ainong REN
;
Yunru PENG
;
Zhigang WANG
;
Miaomiao YAO
;
Ran GAO
;
Houcai HUANG
- Publication Type:Journal Article
- Keywords:
Qingqi Liangying Injection;
hypothalamus;
prostaglandin E_2 (PGE_2);
cAMP;
rat
- From:
Chinese Traditional Patent Medicine
2010;(2):200-202
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of Qingqi Liangying Injection on febrile rats induced by zymonsa and on content of PGE_2 as well as cAMP in rat hypothalamus. METHODS: The rat febrific model induced by 10% zymonsa solution was used to observe QingqiLiangying Injection's effect on the rat temperature, and the radioimmunoassay(RIA) was used to determin the content of PGE_2 and cAMP in hypothalamus of rats. RESULTS: Qingqi Liangying Injection had an obvious antipyretic effect on febrile rats; Qingqi Liangying Injection could significantly reduce the content of PGE_2 and cAMP. CONCLUSION: Qingqi Liangying Injection can obviously reduce the rat body temperature and the content of PGE_2 and cAMP in hypothalamus of rats.
