Clinical observation of Tanreqing Injection in treatment of patients with acute asthma
- VernacularTitle:痰热清佐治支气管哮喘急性发作的疗效分析及机制探讨
- Author:
Jianyong LIN
;
Lanqing MENG
;
Weigui LUO
;
Xingyan LI
- Publication Type:Journal Article
- Keywords:
Tanreqing Injection;
ET;
TNF-α;
acute asthma
- From:
Chinese Traditional Patent Medicine
2010;(2):184-186
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe clinical efficacy of Tanreqing Injection (Radix Scutellariae, Bear gall powder, Ram's horn, Flos lonicerae japonicae and Fructus forsythiae) in treatment of patients with acute attack of bronchial asthma. METHODS: One hundred and seven patients with an acute asthma were randomly assigned into two groups: a treatment group (n=52, treated by Tanreqing Injection for 10 d in addition to the routine medications) and a control group (n=55, treated by routine medications). The serum levels of ET and TNF-α were determined by radioimmunoassay before and after treatment, respectively. RESULTS: Before treatment, there were no significant differences in the content of serum ET and TNF-α between the treatment group and the control group. However, after 10 d of treatment, the levels of ET and TNF-α inthe treatment group were significantly lower than those of the control group (P<0.01), and clinical efficacy of the treatment group was superior to the control group. CONCLUSION: Inhibitionof ET and TNF-α secretion and intervention inflammatory response might be one of mechanisms of Tanreqing Injection in treatment for acute asthma.
