Effect of Sancao prescription extracts on lung adencarcinoma cell line(A549)
- VernacularTitle:三草方提取物对肺腺癌A549细胞的作用
- Author:
Xiaobin JIA
;
Zhenzhong SHAO
;
Yan CHEN
;
Haijian YUAN
;
Xiaoyong JIN
- Publication Type:Journal Article
- Keywords:
Sancao prescription;
extract;
adenocarcinoma of lung;
A549 cells strain
- From:
Chinese Traditional Patent Medicine
2010;(2):196-199
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the ethanolic and aqueous extracts from Sancao prescription (Spica prunellae, Oldenlandia diffuse (willd) Roxb, Herba agrimoniae) on the proliferation of human lung adenocarcinoma cell line (A549). METHODS: 95% ,60% and 30% ethanolic extract and aqueous extract were prepared from Sancao pre-scription. The MTT assay was used to determine the inhibitory action against the proliferation of A549. RESULTS: IC_(50) of 60% ethanolic extract over A549 was one of the lowest in extracts. Combination of 60% and 90% ethanolic extract showed the synergistic antitumour activity. CONCLUSION: Ethanolic extract of Sancao prescription has and effect on human hung adenocarcinoma(A549).
