Comparison of dissolution of asperosaponin Ⅵ between ultra- micro powder and fine powder of Radix Dipsaci
- VernacularTitle:川续断超微粉与普通粉中川续断皂苷Ⅵ溶出特性比较研究
- Author:
Chunfeng ZHANG
;
Kai LI
;
Zhonglin YANG
- Publication Type:Journal Article
- Keywords:
Radix Dipsaci;
ultra- micro powder;
ordinary powder;
asperosaponin Ⅵ;
dissolution property
- From:
Chinese Traditional Patent Medicine
2010;(1):100-102
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To compare the dissolution of asperosaponin Ⅵ between the ultra-micro powder and the fine powder of Radix Dipsaci.METHODS : The real contents,in vitro release and releasing rate of asperosaponin Ⅵ were determined by HPLC for the ultra-micro powder and the fine powder.RESULTS: In the ultra- micro powder and the ordinary powder,the real content of asperosaponin Ⅵ were 4.87%,4.74%,respectively; in vitro release in 1 h were 48.2 mg/g,47.5 mg/g,respectively; releasing rate parameter T_(0.9) were 0.23 min,10.41 min,respectively.CONCLUSION: The ultra- micro porphyrization could not influent the real content and in vitro release of asperosaponin Ⅵ in Radix Dipsaci.But it could improve the releasing rate of asperosaponin Ⅵ.
