Pathological features of tubular carcinoma of 29 cases breast
10.3969/j.issn.1001-7399.2010.01.008
- VernacularTitle:乳腺小管癌29例病理形态学观察
- Author:
Jing LI
;
Guangzhi YANG
;
Huaye DING
- Publication Type:Journal Article
- Keywords:
breast neoplasms/pathology;
tubular carcinoma;
immunohistochemical phenotype
- From:
Chinese Journal of Clinical and Experimental Pathology
2010;(1):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate clinicopathological features,diagnosis and differential diagnosis of tubular carcinoma of the breast.Methods Morphological observation and immunohistochemistry were applied in 29 cases of tubular carcinoma of the breast, and the literatures were also reviewed.Results The tumors were composed of open tubules, infiltrating haphazardly in the cellular desmoplastic stroma. The neoplastic tubules were enclosed by a single layer of epithelial cells with insignificant atypia or rare mitoses.The tumors were often associated with lobular neoplasm, columnar cell lesion, ductal atypical hyperplasia or carcinoma in situ. Immunostaining displayed that myoepithelial cells were absent or incomplete.Conclusions Tubular carcinoma of the breast is a peculiar subtype of breast carcinoma with good prognoses, which is easily confused with microglandular adenosis, radial sclerosing lesions,or low grade invasive ductal carcinoma.Immunohistochemistry is useful for the differential diagnosis.
