The study of growth and development of normal prostate in 3.0 T MRI
10.3760/cma.j.issn.1005-1201.2013.04.013
- VernacularTitle:正常前列腺生长发育的3.0 T MRI研究
- Author:
Huijia LIU
;
Jing REN
;
Yi HUAN
- Publication Type:Journal Article
- Keywords:
Prostate;
Growth;
Magnetic resonance imaging
- From:
Chinese Journal of Radiology
2013;(4):349-351
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prostate volume of normal children and adolescents and to evaluate the development of prostate central zone and peripheral zone.To provide the preliminary MRI standards of prostate growth and development for nomal Chinese children and adolescents.Methods Five hundred and fifty eight healthy male volunteers,aged from 2 to 25 years were retrospectively analysed.They were divided into 5 groups by the ages (group A:2 to 5 years,group B:6 to 10 years,group C:11 to 15 years,group D:16 to 20 years and group E:21 to 25 years).All the volunteers underwent conventional MRI examinations at our institution (T2WI axial and coronal image acquisition).The prostate volume of different age groups were measured,the development of the central zone and peripheral zone were scored by two radiologists,and the datas were treated by Nonparametric test.Results Group A children's prostate nearly not development,only individual MRI measurable its size; Group B most not development,only 6 children visible prostate form,but can't distinguish the anatomical division; Group C prostate gland development better,MRI can measure the size,but distinguish its central and peripheral area is difficult ; Group D prostate gland development rapidly,differences are obvious,but only a few central and peripheral area boundary clear; Group E the central and peripheral area boundary clear,form full,T2 WI signal contrast clear.The median prostate volumes of 5 groups were 0.000,0.000,2.450,7.990 and 10.600 cm3,respectively(x2 =215.452,P ＜ 0.01).The median prostate scores of 5 groups were 0.04,0.31,1.34,2.23 and 2.60,the prostate volumes were significant difference among these 5 groups except group A and group B(x2 =127.460,P ＜0.01),there were significant difference among the volumes and the scores of these five groups (P ＜0.01).Conclusions MRI provided the basis of objective and truth for the the measurements of volume and the observations of prostate development in this study,that offers preliminary reference range for normal Chinese children and adolescents prostate development status.
