Effects of right ventricular septal pacing modes on acute cardiac function and ventricular synchronization in dogs with heart failure
10.3760/cma.j.issn.1008-1372.2013.02.003
- VernacularTitle:右室间隔部起搏对心衰犬心室同步性及心功能的影响
- Author:
Jihong GAN
;
Zhihui HUANG
;
Yinhua JIANG
;
Yana WEI
;
Maoru MA
;
Liqun MA
- Publication Type:Journal Article
- Keywords:
Cardiac pacing,artificial/methods;
Heart failure/therapy;
Disease models,animal;
Ventricular function,left
- From:
Journal of Chinese Physician
2013;(2):153-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate effects of right ventricular septal pacing modes on treatment of heart failure.Methods Twelve dogs with heart failure were performed in every dog at random,and the pacing modes employed in the test included right atrium-right ventricular apex (RVA),right atrium-right ventricular septal(RVS),and right atrium-biventricular (Bi-V) ; The pacing frequency was 180 times per minute.The results were measured before pacing and after 15 minutes when the pacing became stable in Color Doppler echocardiography,including left ventricular end-diastolic diameter (LVEDd),left ventricular ejection fraction (LVEF),interventricular mechanical delay (IVMD),interventricular septum and left ventricular posterior wall motion delay (SPWMD),and left ventricular 12-segment peak time standard deviation (Ts-SD).Results Right ventricular septal pacing mode:(1)Compared with parameter before pacing and RVA pacing,LVEDd,IVMD,SPWMD,and Ts-SD decreased and LVEF increased,and the difference was significant(P ＜0.05).(2)Compared with Bi-V pacing,LVEDd,IVMD,and SPWMDandTs-SD increased and LVEF decreased,and the difference was significant (P ＜ 0.05).Conclusions Right ventricular septal pacing could improve ventricular synchrony and cardiac function partly,and the effect was better than right ventricular apical pacing but less than biventricular pacing,also could not be a alternative models of cardiac resynchronization therapy for heart failure.
