Effect of ginger transderm scopolamine on cerebral ischemia-reperfusion injury
- VernacularTitle:生姜透皮贴对脑缺血再灌注损伤的保护作用研究
- Author:
Zhaochang KANG
;
Mingzhang AO
- Publication Type:Journal Article
- Keywords:
Ginger transderm scopolamine;
Cerebral;
Ischemia-reperfusion injury;
NO;
SOD;
MDA
- From:
Journal of Chinese Physician
2012;(z1):26-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of Ginger Transderm Scopolamine on cerebral ischemia-reperfusion injury.Methods The animals (rats) were divided into three groups randomly:normal contrast group,cerebral ischemia-reperfusion injury group,Ginger Transderm Scopolamine treatment group.The rats of Ginger Transderm Scopolamine group were given by oral gavage once a day.NO,SOD,MDA in brain and cerebral homogenate water content were determined.Results Compared with ceremal ischemia reperfusion group Ginger Transderm Scopolamine could increase the activity of SOD and decrease the level of MDA in brain tissue and brain water content(P ＜ 0.01).Conclusion Ginger Transderm Scopolamine might have a protective effect against the damage of cerebral ischemia-reperfusion injury.
