Retrospective analysis of 58 patients with Takayasu' s arteritis
10.3760/cma.j.issn.1673-4203.2013.01.009
- VernacularTitle:多发性大动脉炎58例回顾性临床分析
- Author:
Hao PAN
;
Chenyang SHEN
- Publication Type:Journal Article
- Keywords:
Takayasu arteritis;
Clinical features;
Sex factors;
Disease activity;
Hypertension;
Prognosis
- From:
International Journal of Surgery
2013;(1):26-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical features and curative effect of patients with Takayasu's arteritis.Methods The clinical data of fifty-eight patients,which were divided into different groups according to gender,clinical classifications,disease activity,and so on,were retrospectively analyzed,to compare whether the results of clinical features,laboratory tests or prognosis had significant differences.Results The data suggested the fact that stroke as first manifestation(2/9 vs 0/49,P =0.022) and incidence of hypertension (9/9 vs 28/49,P =0.037),as well as critical hypertension(8/9 vs 18/49,P =0.011) were more common in male patients than in female patients.The active Takayasu's arteritis patients showed that the level of erythrocyte sedimentation rate (ESR),C-reactive protein (CRP),platelet and fibrinogen was elevated,while the level of Albumin/Globulin ratio was decreased.Electrophoresis showed that the elevation of globulin mainly based on globulin α1 and globulin α2 (P ＜ 0.05).The reduction of complement C3 is more common in inactive group than in active group.Conclusion Stroke and hypertension are more common in male Takayasu's arteritis patients than in female patients.The active Takayasu' s arteritis patients showed elevated level of ESR,CRP,platelet and fibrinogen,while the level of Albumin/Globulin ratio was reduced.
