The change of serum ischemia modified albumin level in continuous ambulatory peritoneal dialysis patients
10.3760/cma.j.issn.1673-4904.2013.06.002
- VernacularTitle:持续不卧床腹膜透析患者血清缺血修饰白蛋白水平变化
- Author:
Xiaoyan SU
;
Weiping ZHENG
;
Xiaodong GUAN
;
Zhaohui ZOU
;
Li CHEN
- Publication Type:Journal Article
- Keywords:
Kidney failure,chronic;
Peritoneal dialysis,continuous ambulatory;
Ischemia modified albumin
- From:
Chinese Journal of Postgraduates of Medicine
2013;(6):3-5
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the change of serum ischemia modified albumin (IMA) in continuous ambulatory peritoneal dialysis (CAPD) patients.Methods Seventy-four end stage renal disease patients undergoing CAPD more than 3 months (CAPD group) were divided into 2 groups according to clinical symptoms of cardiovascular diseases:CAPD symptoms group (29 cases) and CAPD asymptomatic group (45 cases).Seventy healthy subjects were selected as control group.The serum IMA level and abnormal rate of electrocardiogram and heart color ultrasonic were examined and compared.Results The serum IMA level in CAPD group was significantly higher than that in control group [(92.33 ± 17.17) kU/L vs.(69.63 ± 9.24)kU/L,P＜ 0.01].The serum IMA level in CAPD symptoms group was significantly higher than that in CAPD asymptomatic group [(109.37 ± 21.34) kU/L vs.(85.31 ± 8.58) kU/L,P ＜ 0.05].The elevatory rate of serum IMA level and abnormal rate of electrocardiogram and heart color ultrasonic in CAPD symptoms group were significantly higher than those in C APD asymptomatic group [37.9％ (11/29) vs.15.6％(7/45),62.1％ (18/29) vs.22.2％ (10/45),P ＜0.05].Conclusions The serum IMA level in CAPD patients is elevatory.Serum IMA level is significantly higher in CAPD patients with cardiovascular disease clinical symptoms,it can be used for diagnosis of myocardial damage in CAPD patients.
