Prediction of Long-term Response to Cardiac Resynchronization Therapy by Real-time Three-dimensional Echocardiography
- VernacularTitle:实时三维超声心动图预测心脏再同步化治疗长期疗效的临床研究
- Author:
Weidong REN
;
Yangjie XIAO
;
Chunyan MA
;
Shuang LIU
;
Xiuyun LI
- Publication Type:Journal Article
- Keywords:
real-time three-dimensional echocardiography;
cardiac resynchronization therapy;
left ventricular systolic synchrony;
long-term response
- From:
Journal of China Medical University
2010;(9):752-754
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of real-time three-dimensional echocardiography（RT3DE）to predict the long-term response to cardiac resynchronization therapy（CRT）.Methods Twenty-six patients with heart failure were scheduled for CRT.RT3DE was performed before and one year after the pacemaker implantation,and left ventricular（LV）dyssynchrony was defined as the maximum difference（Tmsv 16-Dif）and standard deviation（Tmsv 16-SD）when the minimum systolic volume of 16 segments was reached.Patients were divided into re-sponders and non-responders according to a reduction ≥15 % in LV end-systolic volume（LVESV）after CRT.Results Seventeen patients（65.4 %）were classified as responders.Compared with non-responders,the responders demonstrated a significant increase in LV ejection fraction,and reduction in Tmsv 16-SD.Tmsv 16-SD was a determinant factor for Δ LVESV ≥15%.Tmsv 16-SD 〉3.5% could be employed to evaluate the short-term response to CRT with 80 % sensitivity and 77 % specificity.Conclusions CRT can increase the LV systolic function and synchrony.RT3DE is highly predictive for long-term response to CRT
