Advances in the effects of Th17 cell and follicular helper T cells and their cytokines on common autoimmune diseases
10.3760/cma.j.issn.1673-4408.2013.02.023
- VernacularTitle:Th17、Tfh细胞及其细胞因子在常见自身免疫性疾病中作用的研究进展
- Author:
Chuan GAN
- Publication Type:Journal Article
- Keywords:
Th17 cells;
Follicular helper T cells;
Autoimmune disease;
IL-21
- From:
International Journal of Pediatrics
2013;(2):183-186
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,researches on many autoimmune diseases show that Th17 and follicular helper T cells(Tfh cells) induce the happening of many autoimmune diseases via IL-21,STAT3 or other cytokines and signaling pathway.IL-21,as the common cytokine of Th17 and Tfh cells,plays an important role on their differentiation and development and function playing.This paper reviews the role of Thl7 and Tfh cells as well as their cytokines in myasthenia gravis,systemic lupus erythematosus and inflammaotoy bowel disease.
