A study on correlation between contrast-enhanced sonography and microvessel density in peripheral lung tumor

VernacularTitle:肺外周性肿瘤的超声造影表现与微血管密度相关性的研究
Author: Yuhua QIN ; Bingsheng CAO ; Yuan WANG ; Juan DENG
Publication Type:Journal Article
Keywords: Ultrasonography,interventional; Peripheral lung tumor; Microvessel density
From: Chinese Journal of Postgraduates of Medicine 2013;(8):1-3
CountryChina
Language:Chinese
Abstract: Objective To observe the correlation between contrast-enhanced sonography and microveesel density (MVD) in peripheral lung tumor.Methods Contrast-enhanced sonography was performed in 55 patients with peripheral lung tumor.Among of them,malignant tumor was 40 cases,benign tumor was 15 cases.Analyzed the quantitative parameters (peak intensity,enhanced strength index) by using time-intensity curve (TIC) with computer.MVD was measured by immunohistochemistry after operation.Results The level of MVD in malignant tumor was significantly higher than that in benign tumor [(24.57 ± 5.93)/HP vs.(15.50 ± 2.82)/HP] (P ＜ 0.05).The level of MVD had significant correlation with peak intensity and enhanced strength index (P ＜ 0.01).Conclusions The peak intensity and enhanced strength index have significant correlation with MVD.They are valuable indexes in evaluating angiogenesis in peripheral lung tumor.