Application of neutrophil gelatinase-associated lipocalin in kidney disease
10.3760/cma.j.issn.1673-4408.2013.02.012
- VernacularTitle:肾损伤因子在肾脏疾病中的应用
- Author:
Xiaojin HUANG
- Publication Type:Journal Article
- Keywords:
Neutrophil gelatinase-associated lipocalin;
Acute kidney injury;
Chronic kidney disease;
End-stage renal disease
- From:
International Journal of Pediatrics
2013;(2):145-148
- CountryChina
- Language:Chinese
-
Abstract:
Neutrophil gelatinase-associated lipocalin is a new member of lipocalin family,existing in some normal tissues in human body.During recent years,Some researches have shown that NGAL is associated with kidney disease.NGAL maybe a biomarker which can detect acute kidney injury (AKI) in the early phase compared with serum creatinine,a traditional blood biomarker for diagnosis of AKI.Some researches showed that NGAL also maybe a biomarker that can monitor the progress and treatment effect of chronic kidney disease.In patients with end-stage renal disease,NGAL maybe an index for dialysis adequency.
