Advances in pathogenic mechanism of dilated cardiomyopathy
10.3760/cma.j.issn.1673-4408.2013.02.004
- VernacularTitle:扩张型心肌病致病机制的研究进展
- Author:
Yan LIU
- Publication Type:Journal Article
- Keywords:
Dilated cardiomyopathy;
Vitamin D deficiency;
Gene mutation
- From:
International Journal of Pediatrics
2013;(2):118-121
- CountryChina
- Language:Chinese
-
Abstract:
Dilated cardiomyopathy (DCM) is the most common type of cardiomyopathy in children.It is associated with gene mutation,viral infection,autoimmunity,nutritional deficiency,drug induced,endocrine and metabolic abnormalities,et al.Through the balance of the calcium content,the negative control of renin-angiotensin-aldosterone system and the reduction of the formation of inflammatory mediators,vitamin D can reduce the occurrence of DCM.This paper elaborates the latest research advances of the DCM pathogenesis and treatment,especially focusing on the mechanism and prognosis of vitamin D deficiency and gene mutation.
