Detection of regulatory T lymphocyte in the peripheral blood of lung cancer patients and its clinical significance

VernacularTitle:肺癌患者外周血调节性T淋巴细胞检测及其临床意义
Author: Youjie YU ; Minghua WENG
Publication Type:Journal Article
Keywords: Lung neoplasms; T-lymphocytes,regulatory; Prognosis
From: Chinese Journal of Postgraduates of Medicine 2013;(12):1-2
CountryChina
Language:Chinese
Abstract: Objective To investigate the percent and clinical significance of regulatory T lymphocyte (Treg) in lung cancer patients.Methods Sixty-six cases of lung cancer patients were collected as lung cancer group,30 healthy person were collected as control group.The percent of Treg was detected and contrasted between the two groups.Results The percents of Treg in control group and lung cancer group were 0.0356 ± 0.0122 and 0.1263 ± 0.0318,respectively,there was significant difference between the two groups (P ＜ 0.01).The percent of Treg had no significantly related with gender,age,pathological type in lung cancer patients (P ＞ 0.05).The percent of Treg was significantly related with histological grade and clinical pathological stage (P＜ 0.05 or ＜ 0.01).Conclusion The abnormal elevation of the percent of Treg may be involved in the occurrence and development of lung cancer,and the percent of Treg can be used as the classification and prognosis of lung cancer patients.