Quality control and hot issues of maternal serum prenatal screening in China
10.3760/cma.j.issn.1009-9158.2013.01.001
- VernacularTitle:产前筛查与诊断的质量控制与热点问题
- Author:
Shiming Lü
;
Fengxian SHEN
- Publication Type:Journal Article
- Keywords:
Genetic screening;
Prenatal diagnosis;
Quality control
- From:
Chinese Journal of Laboratory Medicine
2013;(1):1-5
- CountryChina
- Language:Chinese
-
Abstract:
It must be emphasized in the maternal serum prenatal screening that the quality is not only influenced by accuracy of biomarker assay,risk calculation parameters and biomarker database,but also influenced by clinical factors such as gestational weeks,weight and ect.The result of prenatal screening is just a risk evaluation,the subsequent diagnosis and the follow-up are more important.It is expected to improve screening efficiency by localization of prenatal screening database and making the quality management of the prenatal screening-diagnosis suitable for the national conditions.On the other hand,prenatal screening in the women of advanced maternal age and twin pregnancy,improve amniotic fluid cell culture method,chromosome analysis automation,the introduction and positioning of rapid prenatal molecular diagnosis techniques become the hot issues.
