The impact of preoperative portal vein thrombosis on living donor liver transplantation
10.3760/cma.j.issn.1007-631X.2013.03.007
- VernacularTitle:术前门静脉血栓对活体肝移植预后的影响
- Author:
Yonglei WANG
;
Tao YANG
;
Zhijun ZHU
;
Liying SUN
;
Zhigui ZENG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Living donors;
Thrombosis;
Portal vein
- From:
Chinese Journal of General Surgery
2013;(3):189-192
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of preoperative portal vein thrombosis (PPVT) on living donor liver transplantation (LDLT).Methods In this study,99 patients who underwent LDLT by the same surgical team of Tianjin First Centre Hospital from 2007 to 2011 were retrospectively analyzed.According to whether there was a PPVT,all the patients were divided into PPVT group (26 cases) and non-PPVT group (73 cases).The preoperative risk factors and the impact of PPVT on LDLT and outcomes were analyzed.Results Among 26 PPVT patients there were 23 cases in grade Ⅰ and 3 cases in grade Ⅱ.Splenectomy was found to be an independent risk factor for PPVT (x2 =10.211,P =0.001).PPVT prolonged the anhepatic phase (Z =-2.430,P =0.015),but the incidence of surical complications and mortality were no statistical differences between the PVT group and the non-PVT groups.Meanwhile,there was no statistical difference of 1-and 3-year survival rate between the two groups(x2 =0.505,P =0.477).Conclusions With proper intraoperative treatment and postoperative prevention,PPVT does not affect the outcomes of patients suffering from grade Ⅰ or Ⅱ PPVT.However,PPVT added to difficulties of operation,so the detailed preoperative evaluation and careful intraoperative operation is necessary.
