The expression and significance of cyclin E in rectum carcinoma
10.3760/cma.j.issn.1673-4904.2013.03.011
- VernacularTitle:细胞周期素E在直肠癌中的表达及意义
- Author:
Guangming QIN
;
Xiaojun HUANG
;
Yisheng WEI
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Immunohistochemistry;
Cyclin E
- From:
Chinese Journal of Postgraduates of Medicine
2013;(3):30-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and significance of cyclin E in rectum carcinoma.Methods The expression of cyclin E was examined by immunohistochemical techniques in 42 cases of rectum carcinoma.Laboratory data were then analyzed statistically together with the related clinical and pathological data.Results The positive expression rate of cyclin E in rectum carcinoma was 66.7％(28/42).There was no significant association between cyclin E and gender,age,histological grade,pTNM stage,metastasis of lymph node (P ＞ 0.05).Conclusions The expression of cyclin E in rectum carcinoma is higher,and it may show highly associated with the occurrence and development of the rectum carcinoma.Cyclin E has no significant association with age,gender,histological grade,pTNM stage,metastasis of lymph
