The effects of six-minute walking exercise on exercise tolerance and the left ventricular diastolic function of heart failure patients with a normal ejection fraction
10.3760/cma.j.issn.0254-1424.2013.01.005
- VernacularTitle:6分钟步行运动训练对射血分数正常的心力衰竭患者运动耐力及左室舒张功能的影响
- Author:
Zhaoqiang DONG
;
Jing GUO
;
Weidong JIANG
;
Shaojie BI
;
Lin HAO
;
Qinghua LU
- Publication Type:Journal Article
- Keywords:
Heart failure;
Ejection fraction;
Walking;
Exercise;
Brain natriuretic peptide;
Left ventricular diastolytic function
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2013;(1):17-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of 6-minutes of walking exercise (6-MWE) on the exercise tolerance and left ventricular diastolic function (LVDF) of heart failure patients with a normal ejection fraction (HFNEFs).Methods Ninety grade Ⅱ or Ⅲ HFNEFs of the New York heart association (NYHA) were randomly divided into an exercise training group and a control group with 45 cases in each.The control group was treated with routine drugs.The exercise training group was treated with the same drugs plus 6-MWE.Before and after the sixmonth period of treatment,plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were determined,each subject's left atrial volume index (LAVI) was measured with a color ultrasonic cardiogram (UCG),and their 6-minute walk distance (6-MWD) was measured.Results Plasma NT-proBNP levels and 6-MWD improved significantly comparing with before treatment in both groups.The average 6-MWD,LAVI and plasma NT-proBNP level all improved significantly more in the experimental group.Conclusion 6-MWE can significantly improve the exercise tolerance and LVDF of HFNEFs,and improve their quality of life.Walking can be helpful in delaying the development of HFNEF.