Application of extended criteria donor graft in adult cadaveric liver transplant
10.3760/cma.j.issn.1007-631X.2013.03.009
- VernacularTitle:扩大标准的供体肝脏在成人间肝脏移植中的应用
- Author:
Ying WANG
;
Ming QU
;
Yanfen SHI
;
Yingdong DU
;
Huisheng YIN
;
Yanjun LIU
;
Chengjun ZHANG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Risk factors;
Survival rate
- From:
Chinese Journal of General Surgery
2013;(3):196-199
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate extended criteria donor liver in adult cadaveric liver transplant.Methods 126 liver transplantations were performed from January 2003 to June 2009,of them,74 patients received standard criteria donor livers,52 patients received extended criteria donor livers.These 52 donor livers could be divided into two groups:E1 group (a graft with 1 to 2 risk factors) and E2 group(a graft with 3 to 4 risk factors).Results There was no significant difference in half a year and 1 year survival rates between patients received E1 group extended criteria donor livers and those received standard criteria donor livers(respectively x2 =2.55,3.64,all P ＞0.05).But 2 year survival rate of patients received E1 group extended criteria donor livers was lower than those receiving standard criteria donor livers (x2 =4.9,P ＜0.05).Half a year,1 year and 2 year survival rates in patients receiving E2 group extended criteria donor livers were less than those receiving standard criteria donor livers (respectively x2 =3.91,8.67,11.34,all P ＜ 0.05).The half a year,1 year,and 2 year survival rates of patients received extended criteria donor livers with MELD score more than 20 was less than those with MELD score ＜ 20 (respectively x2 =0.16,0.16,0.07,all P ＜ 0.05).Conclusions Extended criteria donor livers can be used safely if the risk factor of donor liver was less than 3,or when recipient's MELD score was ＜20.
