Posttransplant bone metastasis in hepatocellular carcinoma patients receiving liver transplantation

VernacularTitle:肝癌肝移植术后骨转移患者的手术治疗
Author: Zhao LI ; Jie GAO ; Xin SUN ; Guangming LI ; Jiye ZHU
Publication Type:Journal Article
Keywords: Carcinoma hepatocellular; Liver transplantation; Bone metastasis
From: Chinese Journal of General Surgery 2013;(3):193-195
CountryChina
Language:Chinese
Abstract: Objective To analyze clinical features,surgical treatment efficacy and prognostic factors of bone metastasis patients after liver transplantation for hepatocellular carcinoma.Methods A retrospective clinical data of 20 bone metastasis patients after liver transplantation for hepatocellular carcinoma from July 2000 to January 2010 were received.The effect of surgery aimed at bone metastasis was evaluated.Univariate and multivariate prognostic risk factors were analyzed.Results The median survival time of these patients was 7.5 months and 1-year survival rate was only 20％.Surgical treatment could relieve pain and promote patients' peformance status significantly.Univariate and multivariate analysis found that tumor microvascular invasion within the removed recipient liver was the only prognostic risk factor.Conclusions Patients of bone metastasis after liver transplantation for HCC had poor prognosis.Surgical treatment helps improve patient's quality of life.Tumor microvascular invasion is the risk factor of surgical prognosis.