Pathoclinical characteristics of bilateral well-differentiated thyroid carcinoma

VernacularTitle:双侧分化型甲状腺癌的特征因素研究
Author: Ling MA ; Weidong LI ; Peng SONG ; Tong LIU
Publication Type:Journal Article
Keywords: Thyroid neoplasms; Thyroidectomy; Risk factors
From: Chinese Journal of General Surgery 2013;(1):31-34
CountryChina
Language:Chinese
Abstract: Objective To calculate the incidence of pathology-proved bilateral well-differentiated thyroid carcinoma (BWDTC) in patients undergoing total or near total thyroidectomy.Methods Clinical data were retrospectively reviewed in 121 patients who underwent total or near total thyroidectomy.Thirteen indexes selected from both the unilateral thyroid carcinoma group and the bilateral thyroid carcinoma group were adopted to undergo a univariate analysis and Logistic regression analysis.Results BWDTC was found in 33.06％ patients after total or near total thyroidectomy.Logistic regression analysis showed that patient's age ＜ 50,bilateral nodules based on ultrasound and the diameter of the tirst nodule ＞ 2 cm were independent risk factors for BWDTC (P ＜ 0.05).Conclusions In the premise of a malignant first nodule found in the preoperative examinations,BWDTC should be highly suspected if the patient is under 50 years old,has bilateral nodules found by preoperative ultrasound and the diameter of the first malignant nodule is over 2 cm.