Insulin resistance and polycystic ovary syndrome
10.3760/cma.j.issn.1000-6699.2013.03.001
- VernacularTitle:胰岛素抵抗和多囊卵巢综合征
- Author:
Yiming MU
;
Min LIU
- Publication Type:Journal Article
- Keywords:
Insulin resistance;
Polycystic ovary syndrome;
Androgens;
Metabolic syndrome;
Clinical care
- From:
Chinese Journal of Endocrinology and Metabolism
2013;(3):185-188
- CountryChina
- Language:Chinese
-
Abstract:
Insulin resistance likely plays a central pathogenic role in polycystic ovary syndrome and may explain the pleiotropie presentation and involvement of multiple organ systems.Hyperinsulinaemia leads to increased production of androgens resulting in anovulatory infertility.Women,especially those obese women with polycystic ovary syndrome,have an increased risk of developing type 2 diabetes and cardiovascular disease in their later life.Treatment of insulin resistance through lifestyle therapy or with a diabetes drug has become mainstream therapy to reduce the risk of diabetes,endometrial abnormalities,and cardiovascular disease events in women with polycystic ovary syndrome.
