Advances in human placenta-derived stem cells for liver regeneration

VernacularTitle:胎盘源性干细胞在肝脏疾病中的研究进展
Author: Jian WANG ; Zhengyan ZHU ; Zhi DU
Publication Type:Journal Article
Keywords: Human placenta-derived stem cells (hPDSCs); Human placenta mesenchymal stem cells (hPMSCs); Hepatocyte; Regeneration; Apoptosis
From: Chinese Journal of Hepatobiliary Surgery 2013;(3):236-240
CountryChina
Language:Chinese
Abstract: Human placenta-derived stem cells (hPD-SCs) are a mixed group of stem cells.Stem cell medicine has applications for organ damage or failure through regenerative,anti-apoptotic,anti-inflammatory and anti-tumor properties in addition to cell function recovery.Presently,human placenta mesenchymal stem cells (hPMSCs) have similar characteristics to the differentiation of hepatocyte-like cells by promoting hepatocyte regeneration,anti-hepatocyte apoptosis and anti-liver fibrosis,in vitro or in animal models.To further our investigation,a summary of the origin,sorting and biological properties of hPDSCs along with a narration of hPDSCs for liver disease therapy was written.This leads to a discussion for new ideas to further explore cell treatment for liver disease.