Pilot study of the damage degree of Henoch-Schonlein purpura nephritis on children with acoustic radiation force impulse imaging
10.3760/cma.j.issn.1004-4477.2013.01.012
- VernacularTitle:声辐射力脉冲成像对小儿紫癜性肾炎损害程度的初步观察
- Author:
Hu HUANG
;
Fangfang YU
;
Xiaoyu LIN
;
Xiaoxiao XIE
;
Fuguang HUANG
;
Pintong HUANG
;
Qing YANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Purpura nephritis;
Acoustic radiation force impulse imaging
- From:
Chinese Journal of Ultrasonography
2013;(1):42-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of acoustic radiation force impulse (ARFI) imaging in the pathological damage of Henoch-Schonlein purpura nephritis on children by comparison with renal biopsy.Methods 50 cases of healthy control group as group A; 58 children with HSPN were divided into three groups according to pathological grading:Ⅰ ～ Ⅱ class (group B),Ⅲ class (group C) and Ⅳ ～ Ⅵ class (group D).ARFI was then used to measure the shear wave velocities(SWV) of renal cortex of each group,compared the differences SWV of each group.Results SWV values of children's renal cortex with HSPN were significantly higher (t =5.883,P =0.017) than those in the group A.Pairwise comparisons found that there were statistically significant differences between group D and the other three groups (P ＜0.05).According the ROC curve,the cut-off value of SWV was 2.59 m/s when the maximum area under the curve equal to 0.719,the sensitivity and specificity were 63％ and 67％.Conclusions ARFI technology can quantify the elastic properties of the kidney,which is expected as an important indicator to evaluate the pathological extent of damage of the HSPN.
